- Schedule I drug qualifications:
- Intoxicating drug (altered mental and physiological states);
- No accepted medical use;
- High potential for abuse.
- Cannabis and THC (and cannabis extracts) are listed as schedule I on Controlled Substances Act (CSA) I drugs
- EXAMPLE – Schedule III Synthetic THC: Marinol® (24% of synthetic THC in sesame oil) is indicated as Antiemetic – Nausea and vomiting (patients undergoing cancer chemotherapy – Lymphomas), who have failed to respond to conventional antiemetic and appetite stimulant (patients with AIDS)
- Pill form in 2.5, 5, or 10mg doses – maximum typically does not exceed six doses (60mg)/day
- Contraindications: Anyone that has adverse reaction to THC or cannabis, or Marinol.
- Psychotropic effects can last up to four hours and the
- Major side effects
- Mood changes, Dizziness, Drowsiness, Anxiety, Headache, Vomiting, Nausea,Sleep issues, Fainting
- Plant-based medications
- Sativex® (Canada and Europe) for MS, pain, spasticity, advanced cancer
- Epidiolex® (plant-drived cannabidiol, stage III clinical trials; USA) for intractable seizures and epilepsies, Dravet syndrome, Lennox-Gastaut, Infantile spasms
|Schedule 1||Schedule 2||Schedule 3|
|No accepted medical use High abuse potential||Accepted use w/ restrictions High abuse potential||Accepted medical use Some abuse potential|
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